Monday, December 19, 2011

FET #2

Yes, I apologize to anyone following about not posting any sooner, but I did end up with a BFN on FET #1. I went for my beta at 9dp5dt and my HPTs were confirmed... BFN... BIG FAT NEGATIVE. It was very painful and it took some time, but I have moved on and I am ready for FET #2.

We still have 1 frozen XX normal embryo and 17 frozen eggs ready to be fertilized. So I think we are still in pretty good shape. However, some health concerns have arisen over the past few weeks that I am concerned about.

I still have Hashimoto's Thyroiditis like I posted previously, but my TSH levels aren't as low and they would like to see when someone is TTC. So my endocrinologist has upped my Synthroid dose to try to lower the TSH to a better TTC level.

Also, when I failed my first FET, my RE wanted to do some tests to see if we can pinpoint the reason for my failure. First, he had a bunch of levels drawn related to clotting. Then, (at my annual pap with my regular OB Dec 16th) he wrote orders for some cervical cultures (to check for infections), and next week (Dec. 28th) he is going to have my regular OB do an endometrial culture. The endometrial culture is not only to check for uterine infections deep in the endometrium, but also b/c he says that taking a sample irritates the lining and has been shown success in making the lining more lush and rich and better for implantation. So it is supposed to help my embryo implant.

Well, I do not have ALL of the results back yet, but I do have some of the blood work results and so far... not looking great. I have abnormal clotting levels. Indicating I do have some sort of clotting disorder. Now, I have known that I am positive for a genetic disease known as MTHFR deficiency. Dr. T didn't think this would be much of a problem for me, but now that I have 1 failure under my belt he wants to be extra cautious. Well, MTHFR might be impacting my clotting factors more than he thought b/c my clotting levels are so funky. I had some of them re-drawn to check and see if they are always abnormal, but still waiting on the results of the re-draws.

My 2nd FET begins on December 23rd when I start my Lupron (again :-/ ). Oh yeah, and Dr. T made a few changes to my protocol (trying something different in order to hopefully reach a different outcome). Instead of Crinone gel (vaginal cream progesterone), this time I am going to take PIO (progesterone in oil). This is an intramuscular injection that I will take daily at night time. I am definitely NOT looking forward to IM injections daily, and especially nervous that my husband will have to administer them (I cannot reach my own butt!), but I am happy to know that we are doing something different (I don't want another BFN!). Also, since my clotting factors are all coming back abnormal, I am going to have to take Lovenox daily as well. This is a subcutaneous injection I take daily in the belly. Again, not happy to be adding ANOTHER SQ injection (along with Lupron) daily, but prepared to suffer in order to obtain my dream.

So that means that PHASE 1 of FET#2 begins December 23rd with Lupron 10units SQ daily.

Then... I have the PHASE 1 change-up... which is the endometrial biopsy on December 28th.

Then PHASE 2 of FET#2 begins when I start my period again. (approx 2 weeks after starting Lupron) That is when I will begin Estrace pills. I will have my lining check approx 1 week before the slotted transfer date.

Then the final phase, PHASE 3 of FET#2, begins approx 5 days before transfer day. That is when I will start the (FET#2 change-up) PIO injections, (FET#2 change-up) Lovenox injections, Medrol, and Doxycycline.

Then hopefully I can wait at least 7-8 DPT to start POAS. I do not want to POAS at 6dp5dt again. I feel like it was too early. Even though it was BFN 6dp5dt AND 8dp5dt last time... I still don't want to risk testing too early. So I would LOVE to wait until my beta... but I would be happy to make it 7 or 8 days past transfer.

So there you have it!! FET#2 is quickly approaching and I am SOOOO ready for it!!!